How to decide between PRP and PRF
PRP and PRF features and benefits
(use tablet or computer to see table)
Feature/Indication
PRP
PRF
Microneedling
Yes
Inflamatory
Yes
Release of growth factors
Rapid
Over time
Best for
Breaking down tissue
Rebuilding tissue
Hair regeneration
Yes
Use as filler
Yes
Summary
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- Hyperpigmentation
- Acne scars
- Fine lines and superficial wrinkles
- Improving skin texture and radiance
- Post-microneedling or laser for faster recovery
- PRP is rapidly prepared and delivers a quick, concentrated release of growth factors, making it ideal for surface-level rejuvenation and faster visible results.
- It is especially effective for improving skin tone, mild texture issues, and early signs of aging.
- PRP is often used in a series of treatments (typically 3 sessions, spaced 3 months apart) for cumulative improvement1.
- Effects are noticeable within a month but tend to be shorter-lived compared to PRF.
- Best For: Deeper wrinkles and folds
- Facial hollows (under-eye, cheeks, temples)
- Volume loss
- Advanced or long-term skin rejuvenation
- Areas needing sustained collagen stimulation and tissue regeneration
- Surgical recovery and overall facial aesthetics
- The fibrin scaffold acts as a natural filler, providing volume and structure, making PRF ideal for treating deep wrinkles, hollows, and volume loss.
- Results are longer-lasting and more profound, with ongoing improvement in collagen and tissue quality.
- PRF is preferred for patients seeking natural, gradual, and sustained facial rejuvenation without synthetic fillers.
- Choose PRP for rapid improvement in hair regeneration, skin tone, texture, and mild aging signs, especially when you want quick results or are combining with microneedling or laser for enhanced healing and glow.
- Choose PRF for deeper, longer-lasting correction of wrinkles, facial hollows, and more advanced aging, or when you desire natural volume restoration and a gradual, ongoing regenerative effect.
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